Method of Development and Characterization of Pterocarpus Marsupium Loaded Liposomes
Rajat Singh1, Garima Garg, Shivam2
1Rajat Singh, Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Baghpat Bypass, Delhi Roorkee Highway, Meerut (Uttar Pradesh), India.
2Garima Garg, Shivam, Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Baghpat Bypass, Delhi Roorkee Highway, Meerut (Uttar Pradesh), India.
Manuscript received on 28 March 2021 | Revised Manuscript received on 04 April 2021 | Manuscript Accepted on 15 April 2021 | Manuscript published on 30 April 2021 | PP: 11-21 | Volume-1 Issue-1, April 2021 | Retrieval Number: 100.1/ijab.A2004041221
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© The Authors. Published by Lattice Science Publication (LSP). This is an open-access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: The main motive behind this study was to formulate an herbal drug loaded nanosized carrier which enhances the permeability of a hydrophilic herbal drug through the membrane and increases the drug concentration into the systemic circulation. And second motive is to provide a cheap formulation to the future consumers which will be deal with the diabetes on that time. An alternative of that drug was silver nanoparticles present but they are very costly at that time. The effectiveness of the formulation was considered on the basis of the In-Vitro inhibition study of the alpha-amylase by Pterocarpus marsupium loaded liposomes and compared with a positive control Acarbose and it was shows that high concentration of drug was as effective as acarbose to inhibit the alpha – amylase.
Keywords: The drug concentration into the systemic circulation. And second motive is to provide a cheap formulation to the future consumers which will be deal with the diabetes on that time.